The in vitro biomineralization and cytocompatibility of polydopamine coated carbon nanotubes | |
Department | 固体润滑国家重点实验室 |
Yan PH(燕鹏华); Wang JQ(王金清); Wang L(王琳); Liu B(刘斌); Lei ZQ(雷自强); Yang SR(杨生荣) | |
2011 | |
Source Publication | Applied Surface Science |
ISSN | 0169-4332 |
Volume | 257Pages:4849-4855 |
Abstract | In this work, polydopamine coated carbon nanotubeswere firstly prepared by a simple and feasible route. Then, for comparison, the in vitro bioactivity and cytocompatibility of the carbon nanotubes and the polydopamine coated carbon nanotubeswere assessed by immersion study in simulated body fluids and 3-(4,5-dimethyldiazol-2-yl)-2,5-diphenyl tetrazolium bromide test using osteoblast cells (MC3T3-E1), respectively. As a result, it has been demonstrated that the introduction of polydopamine coating can greatly enhance the bioactivity and promote cell proliferation of the carbon nanotubes. The improve- ment of bioactive behavior is attributed to the good combination of catecholamines structure of the polydopamine and the structural advantages of carbon nanotubes as a framework material. It is antici- pated that the polydopamine coated carbon nanotubes would find potential applications in bone tissue engineering and other biomedical areas. |
Keyword | Nanocomposite Materia Carbon Nanotubes Biomineralization Apatite Cytocompatibility |
Subject Area | 材料科学与物理化学 |
Funding Organization | the National Natural Science Foundation of China (Grant NO.50801065);“Top Hundred Talents Program” of Chinese Academy of Sciences |
Indexed By | SCI |
Language | 英语 |
Funding Project | 聚合物摩擦学组 |
Citation statistics | |
Document Type | 期刊论文 |
Identifier | http://ir.licp.cn/handle/362003/673 |
Collection | 固体润滑国家重点实验室(LSL) |
Corresponding Author | Wang JQ(王金清); Yang SR(杨生荣) |
Recommended Citation GB/T 7714 | Yan PH,Wang JQ,Wang L,et al. The in vitro biomineralization and cytocompatibility of polydopamine coated carbon nanotubes[J]. Applied Surface Science,2011,257:4849-4855. |
APA | 燕鹏华,王金清,王琳,刘斌,雷自强,&杨生荣.(2011).The in vitro biomineralization and cytocompatibility of polydopamine coated carbon nanotubes.Applied Surface Science,257,4849-4855. |
MLA | 燕鹏华,et al."The in vitro biomineralization and cytocompatibility of polydopamine coated carbon nanotubes".Applied Surface Science 257(2011):4849-4855. |
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