| Electro-oxidative C(sp3)-H Amination of Azoles via Intermolecular Oxidative C(sp3)-H/N-H Cross-Coupling | |
| Department | OSSO国家重点实验室 |
| Wu, Jiwei1; Zhou, Yi1; Zhou, Yuchen1; Chiang, Chien-Wei1; Lei AW(雷爱文)1,2; Lei AW(雷爱文) | |
| 2017 | |
| Source Publication | ACS Catalysis
 |
| ISSN | 2155-5435 |
| Volume | 7Issue:12Pages:8320-8323 |
| Abstract | A method for electrooxidative C(sp3)–H amination via intermolecular oxidative C(sp3)–H/N–H cross-coupling has been developed under metal- and oxidant-free conditions. The C(sp3)–H bonds adjacent to oxygen, nitrogen, and sulfur atoms could all react smoothly with various amines to give the corresponding products with moderate to good yields (30–93%). In addition, the C(sp3)–H bonds of benzylic and allylic are also tolerated in this reaction. A preliminary mechanistic study indicates that the C–H cleavage of tetrahydrofuran is probably not involved in the rate-determining step. |
| Keyword | Electro-oxidative c(Sp3)-h Amination c(Sp3)-h/n-h Cross-coupling Dehydrogenation External Oxidant Free Azoles |
| Subject Area | 物理化学与绿色催化 |
| DOI | 10.1021/acscatal.7b03551 |
| Funding Organization | the National Natural Science Foundation of China (21390400;21520102003;21272180;21302148);the Hubei Province Natural Science Foundation of China (2013CFA081);the Research Fund for the Doctoral Program of Higher Education of China (20120141130002);the Ministry of Science and Technology of China (2012YQ120060);The Program of Introducing Talents of Discipline to Universities of China (111 Program) |
| Indexed By | SCI |
| Language | 英语 |
| compositor | 第二作者单位 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.licp.cn/handle/362003/23794 |
| Collection | 羰基合成与选择氧化国家重点实验室（OSSO） |
| Corresponding Author | Lei AW(雷爱文) |
| Affiliation | 1.Wuhan Univ, IAS, Coll Chem & Mol Sci, Wuhan 430072, Hubei, Peoples R China 2.Chinese Acad Sci, State Key Lab Oxo Synth & Select Oxidat, Lanzhou Inst Chem Phys, Lanzhou 730000, Gansu, Peoples R China |
| Recommended Citation GB/T 7714 | Wu, Jiwei,Zhou, Yi,Zhou, Yuchen,et al. Electro-oxidative C(sp3)-H Amination of Azoles via Intermolecular Oxidative C(sp3)-H/N-H Cross-Coupling[J]. ACS Catalysis,2017,7(12):8320-8323. |
| APA | Wu, Jiwei,Zhou, Yi,Zhou, Yuchen,Chiang, Chien-Wei,Lei AW,&雷爱文.(2017).Electro-oxidative C(sp3)-H Amination of Azoles via Intermolecular Oxidative C(sp3)-H/N-H Cross-Coupling.ACS Catalysis,7(12),8320-8323. |
| MLA | Wu, Jiwei,et al."Electro-oxidative C(sp3)-H Amination of Azoles via Intermolecular Oxidative C(sp3)-H/N-H Cross-Coupling".ACS Catalysis 7.12(2017):8320-8323. |
| Files in This Item: | ||||||
| File Name/Size | DocType | Version | Access | License | ||
| acscatal.7b03551.pdf（516KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | View Application Full Text | |
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