A Regioselective Synthesis of 2,5-Diaryl Oxazoles via TsOH/I2-Mediated Cascade Cyclization
DepartmentERC国家工程研究中心
Zhang FD(张芳东)1; Wang J(王静)1; Zhang XG(张学国)1; Meng X(孟旭)2; Chen BH(陈保华)1; Chen BH(陈保华)
The second department苏州研究院;osso国家重点实验室
2017
Source PublicationChemistrySelect
ISSN2365-6549
Volume2Issue:28Pages:8717-8720
Abstract

A concise and practical approach for synthesis of 2,5-disubstituted oxazole has been developed via a TsOH(p-Methylbenzene sulfonic acid)/I2-mediated tandem dehydrogenation oxidative cyclization of phenylacetylene and benzylamine. Desired products in high yields have been obtained.

KeywordDehydrogenation Oxidative Cyclization Metal-freecatalyzed Nitrogen Heterocycles Special Decarboxylation
Subject Area物理化学与绿色催化
DOI10.1002/slct.201701390
Funding Organizationthe National Natural Science Foundation of China (Nos. 21372102;21403256)
Language英语
Funding Project催化新工艺研究组
compositor第二作者单位
Citation statistics
Cited Times:8[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.licp.cn/handle/362003/22816
Collection精细石油化工中间体国家工程研究中心(ERC)
羰基合成与选择氧化国家重点实验室(OSSO)
苏州研究院
Corresponding AuthorChen BH(陈保华)
Affiliation1.State Key Laboratory of Applied Organic Chemistry Lanzhou University, Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province Lanzhou 730000, P. R. of China
2.State Key Laboratory for Oxo Synthesis and Selective Oxidation Suzhou Research Institute of LICP, Lanzhou Institute of Chemical Physics (LICP), Chinese Academy of Sciences Lanzhou 730000, P. R. of China
Recommended Citation
GB/T 7714
Zhang FD,Wang J,Zhang XG,et al. A Regioselective Synthesis of 2,5-Diaryl Oxazoles via TsOH/I2-Mediated Cascade Cyclization[J]. ChemistrySelect,2017,2(28):8717-8720.
APA Zhang FD,Wang J,Zhang XG,Meng X,Chen BH,&陈保华.(2017).A Regioselective Synthesis of 2,5-Diaryl Oxazoles via TsOH/I2-Mediated Cascade Cyclization.ChemistrySelect,2(28),8717-8720.
MLA Zhang FD,et al."A Regioselective Synthesis of 2,5-Diaryl Oxazoles via TsOH/I2-Mediated Cascade Cyclization".ChemistrySelect 2.28(2017):8717-8720.
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