| A novel and practical method for the synthesis of dinotefuran through Michael addition of nitromethane to diethyl maleate | |
| Department | OSSO国家重点实验室 |
Li HF(李海峰) ; Wang LL(王来来); Wang LL(王来来)
| |
| 2018 | |
| Source Publication | Tetrahedron
 |
| ISSN | 0040-4020 |
| Volume | 74Issue:2Pages:336-340 |
| Abstract | A novel and practical synthesis of dinotefuran 1, featuring a new access to it from known key intermediate (tetrahydrofuran-3-yl)-methanamine 5, has been achieved through Michael addition reaction of nitromethane to diethyl maleate in 6 steps with 45.5% total yield. This synthesis is scalable and hence has high potential for application to further synthetic elaboration on such new neonicotinoid insecticide dinotefuran 1. |
| Keyword | Dinotefuran Synthesis Mickael Addition Nitromethane Diethyl Maleate |
| Subject Area | 物理化学与绿色催化 |
| DOI | 10.1016/j.tet.2017.12.002 |
| Funding Organization | the National Natural Science Foundation of China (No. 21174155) ; the Youth Foundation of Gansu Province (No. 145RJYA263) |
| Indexed By | SCI |
| If | 2.377 |
| Language | 英语 |
| Funding Project | 有机功能材料研究组 |
| compositor | 第一作者单位 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.licp.cn/handle/362003/22794 |
| Collection | 羰基合成与选择氧化国家重点实验室（OSSO） |
| Corresponding Author | Wang LL(王来来) |
| Affiliation | State Key Laboratory for Oxo Synthesis and Selective Oxidation, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, China |
| Recommended Citation GB/T 7714 | Li HF,Wang LL,Wang LL. A novel and practical method for the synthesis of dinotefuran through Michael addition of nitromethane to diethyl maleate[J]. Tetrahedron,2018,74(2):336-340. |
| APA | Li HF,Wang LL,&Wang LL.(2018).A novel and practical method for the synthesis of dinotefuran through Michael addition of nitromethane to diethyl maleate.Tetrahedron,74(2),336-340. |
| MLA | Li HF,et al."A novel and practical method for the synthesis of dinotefuran through Michael addition of nitromethane to diethyl maleate".Tetrahedron 74.2(2018):336-340. |
| Files in This Item: | ||||||
| File Name/Size | DocType | Version | Access | License | ||
| A novel and practica（701KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | View Application Full Text | |
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