High Strength Astringent Hydrogels Using Protein as the Building Block for Physically Cross-linked Multi-Network | |
Department | 固体润滑国家重点实验室 |
Xu RN(徐蓉年)1,2; Ma SH(麻拴红)1; Lin P(林鹏)1; Yu B(于波)1; Zhou F(周峰)1; Liu WM(刘维民)1; Zhou F(周峰); Liu WM(刘维民) | |
2018-03-07 | |
Source Publication | ACS Applied Materials & Interfaces |
ISSN | 1944-8244 |
Volume | 10Issue:9Pages:7593-7601 |
Abstract | Integrating proteins into a hydrogel network enables its good bioactivity as an ECM environment in biorelative applications. Although extensive studies on preparing protein hydrogels have been carried out, the reported systems commonly present very low mechanical strength and weak water-rentention capacity. Learning from the astringent mouthfeel, we report here a protein engineered multinetwork physical hydrogel as TA-PVA/BSA. In a typical case, the BSA protein-integrated poly(vinyl alcohol) (PVA) solution is treated by the freeze-thaw method and forms the first hydrogel network, and tannic acid (TA) then cross-links with BSA proteins and PVA chains to form the secondary hydrogel network based on the noncovalent interaction (hydrogen bond and hydrophobic interaction). The as-prepared TA-PVA/BSA composite hydrogel is a pure physically cross-linking network and possesses ultrahigh tensile strength up to ∼9.5 MPa but is adjustable, relying on the concentration of TA and BSA. Moreover, its mechanical strength is further improved by prestretching induced anisotropy of mechanical performance. Because of its controllable and layered structure as skin, the composite hydrogel presents good water-retention capacity compared to traditional high strength hydrogels. This work demonstrates a novel method to design high mechanical strength but layered physical cross-linking hydrogels and enables us to realize their biorelative applications. |
Keyword | High Strength Hydrogel Astringent Tannic Acid Protein/pva Noncovalent Interaction |
Subject Area | 材料科学与物理化学 |
DOI | 10.1021/acsami.7b04290 |
Funding Organization | Ministry of Science and Technology (2016YFC1100401);the National Natural Science Foundation of China (51573199;51335010;21434009) |
Indexed By | SCI |
If | 7.504 |
Language | 英语 |
Funding Project | 材料表面界面研究组;空间润滑材料研究组 |
compositor | 第一作者单位 |
Citation statistics | |
Document Type | 期刊论文 |
Identifier | http://ir.licp.cn/handle/362003/22678 |
Collection | 固体润滑国家重点实验室(LSL) |
Corresponding Author | Zhou F(周峰); Liu WM(刘维民) |
Affiliation | 1.State Key Laboratory of Solid Lubrication, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, China 2.College of Materilas Science and Opto-Electonic Technology, University of Chinese Academy of Sciences, Beijing 100049, China |
Recommended Citation GB/T 7714 | Xu RN,Ma SH,Lin P,et al. High Strength Astringent Hydrogels Using Protein as the Building Block for Physically Cross-linked Multi-Network[J]. ACS Applied Materials & Interfaces,2018,10(9):7593-7601. |
APA | Xu RN.,Ma SH.,Lin P.,Yu B.,Zhou F.,...&刘维民.(2018).High Strength Astringent Hydrogels Using Protein as the Building Block for Physically Cross-linked Multi-Network.ACS Applied Materials & Interfaces,10(9),7593-7601. |
MLA | Xu RN,et al."High Strength Astringent Hydrogels Using Protein as the Building Block for Physically Cross-linked Multi-Network".ACS Applied Materials & Interfaces 10.9(2018):7593-7601. |
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High Strength Astrin(6817KB) | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | View Application Full Text |
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