| Bioinspired Total Synthesis of Gymnothelignan N | |
| Department | OSSO国家重点实验室 |
| Li HL(李辉林)1; Zhang, Yuanyuan1; Xie XG(谢新刚)1; Ma, Haichen1; Zhao CG(赵常贵)1; Zhao, Gaoyuan1; She XG(厍学功)1,2; She XG(厍学功) | |
| 2014 | |
| Source Publication | Organic Letters
 |
| ISSN | 1523-7060 |
| Volume | 16Issue:17Pages:4440-4443 |
| Abstract | Bioinspired total synthesis of gymnothelignan N was accomplished in 13 steps and 6.7% overall yield. The synthesis features a syn Evans aldol reaction, an intramolecular hydrogenative dehydration reaction, and a phenol oxidative dearomatization/Friedel-Crafts reaction, which provides a new plausible biosynthetic pathway for the gymnothelignans and other symbiotic members. Meanwhile, another tetrahydrofuran-type lignan beilschmin A was also synthesized. |
| Subject Area | 物理化学与绿色催化 |
| DOI | 10.1021/ol501960j |
| Funding Organization | the NSFC (21125207;21372103);the MOST (2010CB833200);the SRFDP (20130211110018);the FRFCU (lzujbky-2014-240) |
| Indexed By | SCI |
| If | 6.364 |
| Language | 英语 |
| compositor | 第二作者单位 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.licp.cn/handle/362003/20258 |
| Collection | 羰基合成与选择氧化国家重点实验室（OSSO） |
| Corresponding Author | She XG(厍学功) |
| Affiliation | 1.Lanzhou Univ, Dept Chem, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China 2.Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Oxo Synth & Select Oxidat, Lanzhou 730000, Peoples R China |
| Recommended Citation GB/T 7714 | Li HL,Zhang, Yuanyuan,Xie XG,et al. Bioinspired Total Synthesis of Gymnothelignan N[J]. Organic Letters,2014,16(17):4440-4443. |
| APA | Li HL.,Zhang, Yuanyuan.,Xie XG.,Ma, Haichen.,Zhao CG.,...&厍学功.(2014).Bioinspired Total Synthesis of Gymnothelignan N.Organic Letters,16(17),4440-4443. |
| MLA | Li HL,et al."Bioinspired Total Synthesis of Gymnothelignan N".Organic Letters 16.17(2014):4440-4443. |
| Files in This Item: | ||||||
| File Name/Size | DocType | Version | Access | License | ||
| ol501960j.pdf（691KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | View Application Full Text | |
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