Graphene quantum dots as additives in capillary electrophoresis for separation cinnamic acid and its derivatives | |
Department | 中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室 |
Sun YM(孙亚明)1,2,3; Bi, Qing4; Zhang XL(张晓莉)1,2,3; Wang LT(王利涛)1,2; Zhang X(张霞)1,2; Dong SQ(董树清)1,2; Zhao L(赵亮)1,2; Dong SQ(董树清); Zhao L(赵亮) | |
2016 | |
Source Publication | Analytical Biochemistry |
ISSN | 0003-2697 |
Volume | 500Pages:38-44 |
Abstract | A facile capillary electrophoresis (CE) method for the separation of cinnamic acid and its derivatives (3,4-dimethoxycinnamic acid, 4-methoxycinnamic acid, isoferulic acid, sinapic acid, cinnamic acid, ferulic acid, and trans-4-hydroxycinnamic acid) using graphene quantum dots (GQDs) as additives with direct ultraviolet (UV) detection is reported. GQDs were synthesized by chemical oxidization and further purified by a macroporous resin column to remove salts (Na2SO4 and NaNO3) and other impurities. Transmission electron microscopy (TEM) indicated that GQDs have a relatively uniform particle size (2.3 nm). Taking into account the structural features of GQDs, cinnamic acid and its derivatives were adopted as model compounds to investigate whether GQDs can be used to improve CE separations. The separation performance of GQDs used as additives in CE was studied through variations of pH, concentration of the background electrolyte (BGE), and contents of GQDs. The results indicated that excellent separation can be achieved in less than 18 min, which is mainly attributed to the interaction between the analytes and GQDs, especially isoferulic acid, sinapic acid, and cinnamic acid. |
Keyword | Graphene Quantum Dots Additives Capillary Electrophoresis Cinnamic Acid And Its Derivatives |
Subject Area | 分析化学与药物化学 |
DOI | 10.1016/j.ab.2016.01.024 |
Funding Organization | the National Natural Science Foundation of China (21405161;21405162;20675085) |
Indexed By | SCI |
If | 2.334 |
Language | 英语 |
Funding Project | 药物手性分离研究组 |
compositor | 第一作者单位 |
Citation statistics | |
Document Type | 期刊论文 |
Identifier | http://ir.licp.cn/handle/362003/20011 |
Collection | 中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室 |
Corresponding Author | Dong SQ(董树清); Zhao L(赵亮) |
Affiliation | 1.Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Chem Northwestern Plant Resources, Lanzhou 730000, Peoples R China 2.Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Nat Med Gansu Prov, Lanzhou 730000, Peoples R China 3.Chinese Acad Sci, Univ Chinese Acad Sci, Beijing 100049, Peoples R China 4.Northwest Normal Univ, Coll Chem & Chem Engn, Key Lab Bioelectrochem & Environm Anal Gansu Prov, Lanzhou 730000, Peoples R China |
Recommended Citation GB/T 7714 | Sun YM,Bi, Qing,Zhang XL,et al. Graphene quantum dots as additives in capillary electrophoresis for separation cinnamic acid and its derivatives[J]. Analytical Biochemistry,2016,500:38-44. |
APA | Sun YM.,Bi, Qing.,Zhang XL.,Wang LT.,Zhang X.,...&赵亮.(2016).Graphene quantum dots as additives in capillary electrophoresis for separation cinnamic acid and its derivatives.Analytical Biochemistry,500,38-44. |
MLA | Sun YM,et al."Graphene quantum dots as additives in capillary electrophoresis for separation cinnamic acid and its derivatives".Analytical Biochemistry 500(2016):38-44. |
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