| Palladium-Catalyzed Intermolecular Aryldifluoroalkylation of Alkynes | |
| Department | 固体润滑国家重点实验室 |
| He, Yu-Tao1; Wang, Qiang1; Li, Lian-Hua1; Liu XY(刘雪原)1; Xu PF(许鹏飞)1; Liang YM(梁永民)1,2; Liang YM(梁永民) | |
| 2015 | |
| Source Publication | Organic Letters
 |
| ISSN | 1523-7060 |
| Volume | 17Issue:21Pages:5188-5191 |
| Abstract | A palladium-catalyzed aryldifluoroalkylation of alkynes with ethyl difluoroiodoacetate and arylboronic acids as reaction partners is described. The alkyne difunctionalization process provides various aryldifluoroalkylated products in one pot under mild reaction conditions. A wide range of alkynes and diverse arylboronic acids are compatible with these reaction conditions. High reaction efficiency and broad substrate scope are the notable features of this transformation. Preliminary mechanistic investigations indicate that a difluoroalkyl radical addition pathway is involved in this transformation. |
| Subject Area | 材料科学与物理化学 |
| DOI | 10.1021/acs.orglett.5b02512 |
| Funding Organization | the National Natural Science Foundation (NSF 21272101;21472074;21472073);the Fundamental Research Funds for Central Universities (lzujbky-2014-243);the "111" Project (J1103307);Program for Changjiang Scholars and Innovative Research Team in University (IRT1138) |
| Indexed By | SCI |
| If | 6.732 |
| Language | 英语 |
| compositor | 第二作者单位 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.licp.cn/handle/362003/19079 |
| Collection | 固体润滑国家重点实验室（LSL） |
| Corresponding Author | Liang YM(梁永民) |
| Affiliation | 1.Lanzhou Univ, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China 2.Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Solid Lubricat, Lanzhou 730000, Peoples R China |
| Recommended Citation GB/T 7714 | He, Yu-Tao,Wang, Qiang,Li, Lian-Hua,et al. Palladium-Catalyzed Intermolecular Aryldifluoroalkylation of Alkynes[J]. Organic Letters,2015,17(21):5188-5191. |
| APA | He, Yu-Tao.,Wang, Qiang.,Li, Lian-Hua.,Liu XY.,Xu PF.,...&梁永民.(2015).Palladium-Catalyzed Intermolecular Aryldifluoroalkylation of Alkynes.Organic Letters,17(21),5188-5191. |
| MLA | He, Yu-Tao,et al."Palladium-Catalyzed Intermolecular Aryldifluoroalkylation of Alkynes".Organic Letters 17.21(2015):5188-5191. |
| Files in This Item: | ||||||
| File Name/Size | DocType | Version | Access | License | ||
| acs.orglett.5b02512.（942KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | View Application Full Text | |
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