Double-walled hollow polymeric microspheres with independent pH and temperature dual-responsive and magnetic-targeting function from onion-shaped core-shell structures | |
Department | 先进润滑与防护材料研究发展中心 |
Du, Pengcheng1,2; Wang TM(王廷梅)3; Liu P(刘鹏)1,2; Liu P(刘鹏) | |
The second department | 固体润滑国家重点实验室 |
2013 | |
Source Publication | Colloids and Surfaces B: Biointerfaces |
ISSN | 0927-7765 |
Volume | 102Pages:1-8 |
Abstract | The magnetic-targeting stimuli-responsive hollow polymeric microspheres show unique performance as the intelligent carriers for the site specific controlled delivery of drugs or genes. In the work, the well-defied dual-responsive double-walled hollow microspheres with movable magnetic cores were prepared from the penta-layer onion-shaped core-shell microspheres. Their double-walled shells were independent, with the pH-responsive crosslinked poly(methacrylic acid) (PMAA) layer as the inner shell and the temperature responsive crosslinked poly(N-isopropylacrylamide) (PNIPAM) layer as the outer shell. The combination of the pH and temperature dual-responsive and the magnetic-targeting function make the hollow microspheres to be the most promising intelligent carriers in the biomedical fields. |
Subject Area | 材料科学与物理化学 |
DOI | 10.1016/j.colsurfb.2012.07.022 |
Funding Organization | the National Natural Science Foundation of China (Grant No. 20904017);the Program for New Century Excellent Talents in University (Grant No. NCET-09-0441);the Fundamental Research Funds for the Central Universities (Grant No. lzujbky-2012-k12) |
Indexed By | SCI |
If | 4.287 |
Language | 英语 |
Funding Project | 聚合物自润滑复合材料组 |
compositor | 第三作者单位 |
Citation statistics | |
Document Type | 期刊论文 |
Identifier | http://ir.licp.cn/handle/362003/13225 |
Collection | 中国科学院材料磨损与防护重点实验室/先进润滑与防护材料研究发展中心 固体润滑国家重点实验室(LSL) |
Corresponding Author | Liu P(刘鹏) |
Affiliation | 1.Lanzhou Univ, State Key Lab Appl Organ Chem, Coll Chem & Chem Engn, Lanzhou 730000, Peoples R China 2.Lanzhou Univ, Inst Polymer Sci & Engn, Coll Chem & Chem Engn, Lanzhou 730000, Peoples R China 3.Chinese Acad Sci, State Key Lab Solid Lubricat, Lanzhou Inst Chem Phys, Lanzhou 730000, Peoples R China |
Recommended Citation GB/T 7714 | Du, Pengcheng,Wang TM,Liu P,et al. Double-walled hollow polymeric microspheres with independent pH and temperature dual-responsive and magnetic-targeting function from onion-shaped core-shell structures[J]. Colloids and Surfaces B: Biointerfaces,2013,102:1-8. |
APA | Du, Pengcheng,Wang TM,Liu P,&刘鹏.(2013).Double-walled hollow polymeric microspheres with independent pH and temperature dual-responsive and magnetic-targeting function from onion-shaped core-shell structures.Colloids and Surfaces B: Biointerfaces,102,1-8. |
MLA | Du, Pengcheng,et al."Double-walled hollow polymeric microspheres with independent pH and temperature dual-responsive and magnetic-targeting function from onion-shaped core-shell structures".Colloids and Surfaces B: Biointerfaces 102(2013):1-8. |
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Colloids and Surface(903KB) | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | View Application Full Text |
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