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中国科学院兰州化学物理研究所机构知识库
KMS Lanzhou Institute of Chemical Physics,Chinese Academy of Sciences
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中科院西北特色植物资... [9]
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GP-14 protects against severe hypoxia-induced neuronal injury through the AKT and ERK pathways and its induced transcriptome profiling alteration
期刊论文
Toxicology and Applied Pharmacology, 2022, 期号: 448, 页码: 116092
Authors:
Ya-Nan Geng
;
Ming Zhao
;
Jun-Li Yang
;
Xiang Cheng
;
Ying Han
;
Cheng-Bo Wang
;
Xiu-Fang Jiang
;
Ming Fan
;
Ling-Ling Zhu
Adobe PDF(7671Kb)
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Submit date:2022/11/30
Gypenoside-14 (GP-14)
Neuronal Damage
Hypoxia
Transcriptome Sequencing
Neuroprotection
Dammarane Triterpenoids with Rare Skeletons from Gynostemma pentaphyllum and Their Cytotoxic Activities
期刊论文
Fitoterapia, 2022, 期号: 162, 页码: 105280
Authors:
Jun Wang
;
Xian-Hua Meng
;
Wei-Feng Wang
;
Chun-Yan Sang
;
Thi-Kim-Quy Ha
;
Jun-Li Yang
Adobe PDF(1089Kb)
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Submit date:2022/11/30
Gynostemma pentaphyllum (Thunb.) Makino
Cucurbitaceae
Triterpenes, cytotoxic activities
Gyosaponins (GPs) alleviate hypoxia-induced injury in PC12 cells and enhance tolerance to anoxia in C57BL/6 mice
期刊论文
Journal of Food Biochemistry, 2022, 期号: 0, 页码: e14448
Authors:
Cheng-Bo Wang
;
Ming Zhao
;
Jun Wang
;
Jiao-Tai Shi
;
Wei-Feng Wang
;
Ying Zhang
;
Xian-Hua Meng
;
Chun-Yan Sang
;
Ling-Ling Zhu
;
Jun-Li Yang
Adobe PDF(2070Kb)
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Submit date:2022/11/30
Gynostemma pentaphyllum (Thunb.) Makino
gypenosides
high altitude hypoxia
hypoxia tolerance
neuroprotection
A bioactive gypenoside (GP-14) alleviates neuroinflammation and blood brain barrier (BBB) disruption by inhibiting the NF-κB signaling pathway in a mouse high-altitude cerebral edema (HACE) model
期刊论文
International Immunopharmacology, 2022, 期号: 107, 页码: 108675
Authors:
Ya-Nan Geng
;
Jun-Li Yang
;
Xiang Cheng
;
Ying Han
;
Feng Yan
;
Cheng-Bo Wang
;
Xiu-Fang Jiang
;
Xian-Hua Meng
;
Ming Fan
;
Ming Zhao
;
Ling-Ling Zhu
Adobe PDF(8858Kb)
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Submit date:2022/11/30
Gypenoside
Neuroinflammation
Blood brain barrier
High altitude cerebral edema
NF-κB signaling pathway
Cytotoxic Dammarane Triterpenoids from the Hydrolyzate of Gynostemma pentaphyllum
期刊论文
Phytochemistry Letters, 2021, 卷号: 46, 期号: /, 页码: 136-142
Authors:
Wang J(王君)
;
Wang CB(王铖博)
;
Meng XH(孟宪华)
;
Wang WF(王伟峰)
;
Chai T(柴甜)
;
Mahdi Moridi Farimani
;
Yang JL(杨军丽)
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Submit date:2021/11/18
Bungsteroid A: One Unusual C 34 Pentacyclic Steroid Analogue from Zanthoxylum bungeanum Maxim
期刊论文
the Journal of Organic Chemistry, 2020, 卷号: 85, 期号: 16, 页码: 10806−10812
Authors:
Meng XH(孟宪华)
;
Chai T(柴甜)
;
Shi YP(师彦平)
;
Yang JL(杨军丽)
Adobe PDF(1511Kb)
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Submit date:2020/11/16
Zanthoxylum bungeanum Maxim
quantum-chemical 13C NMR
ECD
antiproliferative effect
steroid
Triterpenoids from the genus Gynostemma: Chemistry and pharmacological activities
期刊论文
Journal of Ethnopharmacology, 2020, 卷号: -, 期号: -, 页码: -
Authors:
Author links open overlay panelHieuNguyen-Ngoc
;
Thi KimQuy Ha
;
Yang JL(杨军丽)
;
Ha ThanhTung Pham
;
Won KeunOh
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Submit date:2020/11/16
Gynostemma
phytochemistry
pharmacology
traditional usage
saponin
triterpenoid
Dammarane-Type Saponins from Gynostemma pentaphyllum Prevent Hypoxia-Induced Neural Injury through Activation of ERK, Akt, and CREB Pathways
期刊论文
Journal of Agricultural and Food Chemistry, 2020, 卷号: 68, 期号: 1, 页码: 193−205
Authors:
Wang J(王君)
;
Zhao M(赵名)
;
Xiang Cheng
;
Ying Han
;
Tong Zhao
;
Ming Fan
;
Zhu LL(朱玲玲)
;
Yang JL(杨军丽)
Adobe PDF(4556Kb)
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Submit date:2020/11/16
Gynostemma pentaphyllum
dammarane-type saponins
hypoxia-induced neural injury
Hypoglycemic Triterpenes from Gynostemma pentaphyllum
期刊论文
Phytochemistry, 2018, 卷号: 155, 期号: -, 页码: 171-181
Authors:
Wang, Jun(王君)
;
Ha, Thi Kim Quy
;
Shi, Yan-Ping(师彦平)
;
Oh, Won Keun
;
Yang, Jun-Li
Adobe PDF(1090Kb)
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Submit date:2018/08/26
Gynostemma Pentaphyllum
Cucurbitaceae
Triterpenes
Insulin Mimetic Activity
Further New Gypenosides from Jiaogulan (Gynostemma pentaphyllum)
期刊论文
Journal of Agricultural and Food Chemistry, 2017, 卷号: 65, 期号: 29, 页码: 5926-5934
Authors:
Wang J(王君)
;
Yang JL(杨军丽)
;
Zhou, Pan-Pan
;
Meng XH(孟宪华)
;
Shi YP(师彦平)
;
Yang JL(杨军丽)
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Submit date:2017/11/24
Jiaogulan
Gynostemma Pentaphyllum
New Gypenosides
Ptp1b Inhibitory Activity
Cytotoxicity