| Fabrication of functional block copolymer grafted superparamagnetic nanoparticles for targeted and controlled drug delivery | |
| Department | 固体润滑国家重点实验室 ; 先进润滑与防护材料研究发展中心 |
Mu B(慕斌); Wang TM(王廷梅) ; Wu ZH(吴珍华); Shi HG(石辉刚); Xue DS(薛德生); Liu P(刘鹏)
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| 2011 | |
| Source Publication | Colloids and Surfaces A: Physicochem. Eng. Aspects
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| ISSN | 0927-7757 |
| Volume | 375Pages:163-168 |
| Abstract | The functional block copolymer (poly(hydroyethyl acrylate-b-N-isopropylacrylamide), P(HEA-b- NIPAm)) grafted Fe3O4 nanoparticles (Fe3O4@P(HEA-b-NIPAm)) with temperature-responsive poly(N- isopropylacrylamide) (PNIPAm) as the skin layer were designed via the consecutive surface-initiated atom transfer radical polymerization (SI-ATRP) from the surfaces of the superparamagnetic Fe3O4 nanoparticles. The targeted functional and temperature-sensitive nanoparticles were characterized by the FT-IR, XPS, TEM, VSM, andDLS techniques. It is expected that themulti-functional nanoparticles could be used for the targeted and controlled drug delivery. |
| Keyword | Superparamagnetic Nanoparticle Block Copolymer Environmental Responsive Surface-initiated Atom Transfer Radical Polymerization Drug Delivery |
| Subject Area | 材料科学与物理化学 |
| Funding Organization | the National Nature Science Foundation of China(Grant NO.20904017);Program for New Century Excellent Talents in University (Grant NO.NCET-09-0441);the National Science Foundation for Fostering Talents in Basic Research of the National Natural Science Foundation of China (Grant NO.J0730425) |
| Indexed By | SCI |
| Language | 英语 |
| Funding Project | 聚合物自润滑复合材料组 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.licp.cn/handle/362003/700 |
| Collection | 固体润滑国家重点实验室（LSL） 中国科学院材料磨损与防护重点实验室/先进润滑与防护材料研究发展中心 |
| Corresponding Author | Liu P(刘鹏) |
| Recommended Citation GB/T 7714 | Mu B,Wang TM,Wu ZH,et al. Fabrication of functional block copolymer grafted superparamagnetic nanoparticles for targeted and controlled drug delivery[J]. Colloids and Surfaces A: Physicochem. Eng. Aspects,2011,375:163-168. |
| APA | 慕斌,王廷梅,吴珍华,石辉刚,薛德生,&刘鹏.(2011).Fabrication of functional block copolymer grafted superparamagnetic nanoparticles for targeted and controlled drug delivery.Colloids and Surfaces A: Physicochem. Eng. Aspects,375,163-168. |
| MLA | 慕斌,et al."Fabrication of functional block copolymer grafted superparamagnetic nanoparticles for targeted and controlled drug delivery".Colloids and Surfaces A: Physicochem. Eng. Aspects 375(2011):163-168. |
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| 2011163-168.PDF（823KB） | 开放获取 | License | View Application Full Text | |||
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