Phytotoxic flavonoids from roots of Stellera chamaejasme L. (Thymelaeaceae) | |
Department | 中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室 |
Yan ZQ(燕志强)1; Guo HR(郭鸿儒)1; Yang JY(杨甲月)1; Liu Q(刘权)1; Jin H(金辉)1; Xu R(徐蕊)1; Cui HY(崔海燕)1; Qin B(秦波)1,2; Qin B(秦波) | |
2014 | |
Source Publication | Phytochemistry |
ISSN | 0031-9422 |
Volume | 106Pages:61-68 |
Abstract | Allelopathy, the negative effect on plants of chemicals released to the surroundings by a neighboring plant, is an important factor which contributes to the spread of some weeds in plant communities. In this field, Stellera chamaejasme L. (Thymelaeaceae) is one of the most toxic and ecologically-threatening weeds in some of the grasslands of north and west China. Bioassay-guided fractionation of root extracts of this plant led to the isolation of eight flavonoids 1–8, whose structures were elucidated by spectroscopic analysis. All compounds obtained, except 7-methoxylneochaejasmin A (4) and (+)-epiafzelechin (5), showed strong phytotoxic activity against Arabidopsis thaliana seedlings. Seedling growth was reduced by neochamaejasmin B (1), mesoneochamaejasmin A (2), chamaejasmenin C (3), genkwanol A (6), daphnodorin B (7) and dihydrodaphnodorin B (8) with IC50 values of 6.9, 12.1, 43.2, 74.8, 7.1 and 27.3 μg/mL, respectively, and all of these compounds disrupted root development. Endogenous auxin levels at the root tips of the A. thaliana DR5::GUS transgenic line were largely reduced by compounds 1, 2 and 6–8, and were increased by compound 4. Moreover, the inhibition rate of A. thaliana auxin transport mutants pin2 and aux1–7 by compounds 1–8 were all lower than the wild type (Col-0). The influence of these compounds on endogenous auxin distribution is thus proposed as a critical factor for the phytotoxic effect. Compounds 1, 2, 4 and 8 were found in soils associated with S. chamaejasme, and these flavonoids also showed phytotoxicity to Clinelymus nutans L., an associated weed of S. chamaejasme. These results indicated that some phytotoxic compounds from roots of S. chamaejasme may be involved in the potential allelopathic behavior of this widespread weed. |
Keyword | SteL.era Chamaejasme L. Thymelaeaceae Roots Flavonoids Phytotoxicity Arabidopsis Thaliana Brassicaceae Auxin Soil |
Subject Area | 植物化学生态研究 |
DOI | 10.1016/j.phytochem.2014.07.013 |
Funding Organization | National Natural Science Foundation of China (No. 31070386);Open Fund of State Key Laboratory of Applied Organic Chemistry, Lanzhou University;Basic Research Program of Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences (No. 080423SYR1) |
Indexed By | SCI |
If | 2.547 |
Language | 英语 |
Funding Project | 植物化学生态研究组 |
compositor | 第一作者单位 |
Citation statistics | |
Document Type | 期刊论文 |
Identifier | http://ir.licp.cn/handle/362003/6946 |
Collection | 中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室 |
Corresponding Author | Qin B(秦波) |
Affiliation | 1.Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, PR China 2.State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, PR China |
Recommended Citation GB/T 7714 | Yan ZQ,Guo HR,Yang JY,et al. Phytotoxic flavonoids from roots of Stellera chamaejasme L. (Thymelaeaceae)[J]. Phytochemistry,2014,106:61-68. |
APA | Yan ZQ.,Guo HR.,Yang JY.,Liu Q.,Jin H.,...&秦波.(2014).Phytotoxic flavonoids from roots of Stellera chamaejasme L. (Thymelaeaceae).Phytochemistry,106,61-68. |
MLA | Yan ZQ,et al."Phytotoxic flavonoids from roots of Stellera chamaejasme L. (Thymelaeaceae)".Phytochemistry 106(2014):61-68. |
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