New cytotoxic steroids from the leaves of Clerodendrum trichotomum | |
Department | 中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室 |
Xu RL(徐瑞兰)1,2,3; Wang R(王瑞)1,2; Ding L(丁兰)4; Shi YP(师彦平)1,2; Shi YP(师彦平) | |
2013 | |
Source Publication | Steroids |
ISSN | 0039-128X |
Volume | 78Issue:7Pages:711-716 |
Abstract | A phytochemical investigation of the leaves of Clerodendrum trichotomum led to the isolation of five new (2-6) and two known (1 and 7) steroids, whose structures and relative configurations were elucidated by comprehensive spectroscopic analysis and by comparison of their NMR data with those of related compounds. Steroids 2 and 5 exhibited moderate cytotoxicity in vitro against HeLa cell line. |
Keyword | Clerodendrum Trichotomum Cytotoxicity Steroid |
Subject Area | 分析化学与药物化学 |
DOI | 10.1016/j.steroids.2013.03.002 |
Funding Organization | the Key Directional Project of the Chinese Academy of Sciences (No. KSCX2-EW-R-15);the National Natural Science Foundation of China (No. 21075127) |
Indexed By | SCI |
If | 2.716 |
Language | 英语 |
Funding Project | 药物化学成分研究组 |
compositor | 第一作者单位 |
Citation statistics | |
Document Type | 期刊论文 |
Identifier | http://ir.licp.cn/handle/362003/4643 |
Collection | 中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室 |
Corresponding Author | Shi YP(师彦平) |
Affiliation | 1.Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Chem Northwestern Plant Resources, Lanzhou 730000, Peoples R China 2.Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Nat Med Gansu Prov, Lanzhou 730000, Peoples R China 3.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China 4.Northwest Normal Univ, Coll Life Sci, Lanzhou 730070, Peoples R China |
Recommended Citation GB/T 7714 | Xu RL,Wang R,Ding L,et al. New cytotoxic steroids from the leaves of Clerodendrum trichotomum[J]. Steroids,2013,78(7):711-716. |
APA | Xu RL,Wang R,Ding L,Shi YP,&师彦平.(2013).New cytotoxic steroids from the leaves of Clerodendrum trichotomum.Steroids,78(7),711-716. |
MLA | Xu RL,et al."New cytotoxic steroids from the leaves of Clerodendrum trichotomum".Steroids 78.7(2013):711-716. |
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1-s2.0-S0039128X1300(490KB) | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | View Application Full Text |
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