New cytotoxic steroids from the leaves of Clerodendrum trichotomum
Department中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室
Xu RL(徐瑞兰)1,2,3; Wang R(王瑞)1,2; Ding L(丁兰)4; Shi YP(师彦平)1,2; Shi YP(师彦平)
2013
Source PublicationSteroids
ISSN0039-128X
Volume78Issue:7Pages:711-716
AbstractA phytochemical investigation of the leaves of Clerodendrum trichotomum led to the isolation of five new (2-6) and two known (1 and 7) steroids, whose structures and relative configurations were elucidated by comprehensive spectroscopic analysis and by comparison of their NMR data with those of related compounds. Steroids 2 and 5 exhibited moderate cytotoxicity in vitro against HeLa cell line.
KeywordClerodendrum Trichotomum Cytotoxicity Steroid
Subject Area分析化学与药物化学
DOI10.1016/j.steroids.2013.03.002
Funding Organizationthe Key Directional Project of the Chinese Academy of Sciences (No. KSCX2-EW-R-15);the National Natural Science Foundation of China (No. 21075127)
Indexed BySCI
If2.716
Language英语
Funding Project药物化学成分研究组
compositor第一作者单位
Citation statistics
Cited Times:14[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.licp.cn/handle/362003/4643
Collection中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室
Corresponding AuthorShi YP(师彦平)
Affiliation1.Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Chem Northwestern Plant Resources, Lanzhou 730000, Peoples R China
2.Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Nat Med Gansu Prov, Lanzhou 730000, Peoples R China
3.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China
4.Northwest Normal Univ, Coll Life Sci, Lanzhou 730070, Peoples R China
Recommended Citation
GB/T 7714
Xu RL,Wang R,Ding L,et al. New cytotoxic steroids from the leaves of Clerodendrum trichotomum[J]. Steroids,2013,78(7):711-716.
APA Xu RL,Wang R,Ding L,Shi YP,&师彦平.(2013).New cytotoxic steroids from the leaves of Clerodendrum trichotomum.Steroids,78(7),711-716.
MLA Xu RL,et al."New cytotoxic steroids from the leaves of Clerodendrum trichotomum".Steroids 78.7(2013):711-716.
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