| Efficient and Regioselective Synthesis of 5-Hydroxy-2-isoxazolines: Versatile Synthons for Isoxazoles, β-Lactams, and γ-Amino Alcohols | |
| Department | 羰基合成与选择氧化国家重点实验室 |
| Tang SB(唐仕兵); He JM(何金梅); Sun YQ(孙永权); He LE(何六二); She XG(厍学功) | |
| 2010 | |
| Source Publication | J. Org. Chem.
 |
| ISSN | 1520-6904 |
| Volume | 75Issue:6Pages:1961-1966 |
| Abstract | An efficient and highly regioselective protocol was developed for the preparation of 5-hydroxy-2-isoxazolines, which have been proved to be versatile synthons for isoxazles, β-hydroxy oximes, and γ-amino alcohols. β-Lactams, commonly embedded in the skeletons of bioactive natural products, were also synthesized in two steps from β-hydroxy oximes, providing a new strategy for the synthesis of this kind of compounds. |
| Subject Area | 物理化学 |
| Funding Organization | the generous financial support by the NSFC (QT program, 20872054 and 20732002) |
| Indexed By | SCI |
| Language | 英语 |
| Document Type | 期刊论文 |
| Identifier | http://ir.licp.cn/handle/362003/440 |
| Collection | 羰基合成与选择氧化国家重点实验室（OSSO） |
| Corresponding Author | She XG(厍学功) |
| Recommended Citation GB/T 7714 | Tang SB,He JM,Sun YQ,et al. Efficient and Regioselective Synthesis of 5-Hydroxy-2-isoxazolines: Versatile Synthons for Isoxazoles, β-Lactams, and γ-Amino Alcohols[J]. J. Org. Chem.,2010,75(6):1961-1966. |
| APA | 唐仕兵,何金梅,孙永权,何六二,&厍学功.(2010).Efficient and Regioselective Synthesis of 5-Hydroxy-2-isoxazolines: Versatile Synthons for Isoxazoles, β-Lactams, and γ-Amino Alcohols.J. Org. Chem.,75(6),1961-1966. |
| MLA | 唐仕兵,et al."Efficient and Regioselective Synthesis of 5-Hydroxy-2-isoxazolines: Versatile Synthons for Isoxazoles, β-Lactams, and γ-Amino Alcohols".J. Org. Chem. 75.6(2010):1961-1966. |
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