| Palladium-Catalyzed Vinylation of Aminals with Simple Alkenes: A New Strategy To Construct Allylamines | |
| Department | OSSO国家重点实验室 |
Xie YJ(谢银君); Hu JH(胡建华); Wang YY(王艳预); Xia CG(夏春谷) ; Huang HM(黄汉民); Huang HM(黄汉民)
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| 2012 | |
| Source Publication | Journal of the American Chemical Society
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| ISSN | 0002-7863 |
| Volume | 134Issue:51Pages:20613-20616 |
| Abstract | A novel, highly selective palladium-catalyzed vinylation reaction for the direct synthesis of allylic amines from styrenes and aminals has been established. The utility of this method was also demonstrated by the rapid synthesis of cinnarizine from aldehydes, amines, and simple alkenes in one-pot manner. Mechanistic studies suggested that the reaction proceeds through a valuable cyclometalated Pd(II) complex generated by the oxidative addition of aminal to a Pd(0) species. |
| Subject Area | 物理化学与绿色催化 |
| DOI | 10.1021/ja310848x |
| Funding Organization | the Chinese Academy of Sciences and the National Natural Science Foundation of China (21222203;21172226;21133011) |
| Indexed By | SCI |
| If | 10.677 |
| Language | 英语 |
| Funding Project | 有机功能材料研究组;均相催化课题组 |
| compositor | 第一作者单位 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.licp.cn/handle/362003/3790 |
| Collection | 羰基合成与选择氧化国家重点实验室（OSSO） |
| Corresponding Author | Huang HM(黄汉民) |
| Affiliation | Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Oxo Synth & Select Oxidat, Lanzhou 730000, Peoples R China |
| Recommended Citation GB/T 7714 | Xie YJ,Hu JH,Wang YY,et al. Palladium-Catalyzed Vinylation of Aminals with Simple Alkenes: A New Strategy To Construct Allylamines[J]. Journal of the American Chemical Society,2012,134(51):20613-20616. |
| APA | Xie YJ,Hu JH,Wang YY,Xia CG,Huang HM,&黄汉民.(2012).Palladium-Catalyzed Vinylation of Aminals with Simple Alkenes: A New Strategy To Construct Allylamines.Journal of the American Chemical Society,134(51),20613-20616. |
| MLA | Xie YJ,et al."Palladium-Catalyzed Vinylation of Aminals with Simple Alkenes: A New Strategy To Construct Allylamines".Journal of the American Chemical Society 134.51(2012):20613-20616. |
| Files in This Item: | ||||||
| File Name/Size | DocType | Version | Access | License | ||
| 10.J. Am. Chem. Soc.（331KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | View Application Full Text | |
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