Deconstructive di-functionalization of unstrained, benzo cyclic amines by C–N bond cleavage using a recyclable tungsten catalyst | |
Department | OSSO国家重点实验室 |
Zhang, Yujing; Sun, Shuai; Su, Yijin; Zhao, Jian; Li, Yong-Hong; Han, Bo; Shi, Feng | |
The second department | 石峰研究员课题组;苏毅进人才团队 |
2019 | |
Source Publication | Org. Biomol. Chem. |
Volume | 17Issue:17Pages:4970-4974 |
Abstract | With H2WO4 as the catalyst and H2O2 as the oxidant, we herein report a deconstructive difunctionalization of the C–N bond in unstrained, benzo cyclic amines to generate an ester group and nitro group simultaneously. The preliminary mechanistic studies suggested that the corresponding hydroxamic acid is the key intermediate for this transformation. Importantly, with the utilization of this transformation, we achieved an interesting approach for the ring contraction of quinoline to indole, an example of scaffold hopping in a hetero-aromatic system. |
Keyword | tungsten catalyst oxidation |
MOST Discipline Catalogue | 理学::化学 |
DOI | 10.1039/C9OB00693A |
URL | 查看原文 |
Indexed By | SCI |
If | 3.490 |
Language | 英语 |
compositor | 第一作者单位 |
Citation statistics | |
Document Type | 期刊论文 |
Identifier | http://ir.licp.cn/handle/362003/25563 |
Collection | 羰基合成与选择氧化国家重点实验室(OSSO) |
Corresponding Author | Su, Yijin; Shi, Feng |
Affiliation | 中国科学院兰州化学物理研究所 |
Recommended Citation GB/T 7714 | Zhang, Yujing,Sun, Shuai,Su, Yijin,等. Deconstructive di-functionalization of unstrained, benzo cyclic amines by C–N bond cleavage using a recyclable tungsten catalyst[J]. Org. Biomol. Chem.,2019,17(17):4970-4974. |
APA | Zhang, Yujing.,Sun, Shuai.,Su, Yijin.,Zhao, Jian.,Li, Yong-Hong.,...&Shi, Feng.(2019).Deconstructive di-functionalization of unstrained, benzo cyclic amines by C–N bond cleavage using a recyclable tungsten catalyst.Org. Biomol. Chem.,17(17),4970-4974. |
MLA | Zhang, Yujing,et al."Deconstructive di-functionalization of unstrained, benzo cyclic amines by C–N bond cleavage using a recyclable tungsten catalyst".Org. Biomol. Chem. 17.17(2019):4970-4974. |
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