| The Deracemization of Secondary Alcohols via a Chemo-Enzymatic Process | |
| Department | 羰基合成与选择氧化国家重点实验室 |
Wu XM(吴小梅); Xin JY(辛嘉英); Zhu LM(朱利民); Chris Branford-white; Sun W(孙伟) ; Xu JH(许建和); Xia CG(夏春谷)
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| 2008 | |
| Source Publication | Letters in Organic Chemistry
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| ISSN | 1570-1786 |
| Volume | 5Issue:8Pages:672-675 |
| Abstract | Optically pure secondary alcohols were efficiently prepared via a two-step, one-pot process involving a chemical oxidative agent in combination with an enantioselective ketone reducase Rhodotorula sp. AS2.2241 in tandem. The reaction proceeded successfully with 88~99.5% enantiomeric excess in moderate to good conversions. A variety of substrates, including aromatic and aliphatic alcohols, could be tolerated. |
| Keyword | Deracemization Oxidative Agent Rhodotorula Sp. As2.2241 Chemo-enzymatic One-pot Secondary Alcohols |
| Subject Area | 清洁催化与生物转化 |
| Funding Organization | the NSFC (20625308;20643008);Chinese Academy of Sciences |
| Indexed By | SCI |
| Language | 英语 |
| Funding Project | 清洁催化与生物转化研究组 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.licp.cn/handle/362003/2355 |
| Collection | 羰基合成与选择氧化国家重点实验室（OSSO） |
| Corresponding Author | Sun W(孙伟); Xia CG(夏春谷) |
| Recommended Citation GB/T 7714 | Wu XM,Xin JY,Zhu LM,et al. The Deracemization of Secondary Alcohols via a Chemo-Enzymatic Process[J]. Letters in Organic Chemistry,2008,5(8):672-675. |
| APA | 吴小梅.,辛嘉英.,朱利民.,Chris Branford-white.,孙伟.,...&夏春谷.(2008).The Deracemization of Secondary Alcohols via a Chemo-Enzymatic Process.Letters in Organic Chemistry,5(8),672-675. |
| MLA | 吴小梅,et al."The Deracemization of Secondary Alcohols via a Chemo-Enzymatic Process".Letters in Organic Chemistry 5.8(2008):672-675. |
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