Visible-Light-Mediated Anti-Markovnikov Hydration of Olefins | |
Department | OSSO国家重点实验室 |
Hu, Xia1; Zhang, Guoting1; Bu, Faxiang1; Lei AW(雷爱文)1,2; Lei AW(雷爱文) | |
2017 | |
Source Publication | ACS Catalysis |
ISSN | 2155-5435 |
Volume | 7Issue:2Pages:1432-1437 |
Abstract | Considering that stoichiometric borane and oxidant are required in the classical alkene anti-Markovnikov hydration process, it remains appealing to achieve the transformation in a catalytic protocol. Herein, a visible-light-mediated anti-Markovnikov addition of water to alkenes by using an organic photoredox catalyst in conjunction with a redox-active hydrogen atom donor was developed, which avoided the need for a transition-metal catalyst, stoichiometric borane, as well as oxidant. Both terminal and internal olefins are readily accommodated in this transformation to obtain corresponding primary and secondary alcohols in good yields with single regioselectivity. This procedure can be scaled up to gram scale with a 230 turnover number based on photocatalyst. |
Keyword | Photochemistry Hydration Anti-markovnikov Alkene Alcohol Radical |
Subject Area | 物理化学与绿色催化 |
DOI | 10.1021/acscatal.6b03388 |
Funding Organization | the National Natural Science Foundation of China (21390400;21520102003;21272180;21302148);the Hubei Province Natural Science Foundation of China (2013CFA081);the Research Fund for the Doctoral Program of Higher Education of China (20120141130002);the Ministry of Science and Technology of China (2012YQ120060);the Program of Introducing Talents of Discipline to Universities of China (111 Program) |
Indexed By | SCI |
If | 10.614 |
Language | 英语 |
compositor | 第二作者单位 |
Citation statistics | |
Document Type | 期刊论文 |
Identifier | http://ir.licp.cn/handle/362003/21471 |
Collection | 羰基合成与选择氧化国家重点实验室(OSSO) |
Corresponding Author | Lei AW(雷爱文) |
Affiliation | 1.Wuhan Univ, Inst Adv Studies, Coll Chem & Mol Sci, Wuhan 430072, Hubei, Peoples R China 2.Chinese Acad Sci, Lanzhou Inst Chem Phys, Lanzhou 730000, Peoples R China |
Recommended Citation GB/T 7714 | Hu, Xia,Zhang, Guoting,Bu, Faxiang,et al. Visible-Light-Mediated Anti-Markovnikov Hydration of Olefins[J]. ACS Catalysis,2017,7(2):1432-1437. |
APA | Hu, Xia,Zhang, Guoting,Bu, Faxiang,Lei AW,&雷爱文.(2017).Visible-Light-Mediated Anti-Markovnikov Hydration of Olefins.ACS Catalysis,7(2),1432-1437. |
MLA | Hu, Xia,et al."Visible-Light-Mediated Anti-Markovnikov Hydration of Olefins".ACS Catalysis 7.2(2017):1432-1437. |
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acscatal.6b03388.pdf(1284KB) | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | View Application Full Text |
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