| Three-Component Povarov Reaction with Alcohols as Alkene Precursors: Efficient Access to 2-Arylquinolines | |
| Department | OSSO国家重点实验室 |
Li XJ(李新建)1,2; Xing Q(邢琦)1 ; Li P(李盼)1; Zhao JJ(赵静静)1; Li FW(李福伟)1; Li FW(李福伟)
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| The second department | 苏州研究院 |
| 2017 | |
| Source Publication | European Journal of Organic Chemistry
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| ISSN | 1434-193X |
| Volume | 2017Issue:3Pages:618-625 |
| Abstract | An atom-economic and efficient approach to the synthesis of 2-arylquinolines has been developed. The protocol involves an iron-catalysed cascade N-alkylation/aerobic oxidation/Povarov reaction, and the desired quinolines were prepared in moderate to excellent yields from readily accessible anilines, aldehydes, and EtOH/nPrOH, with water as the only side-product. The aniline substrates also act as a recyclable transfer medium for EtOH/nPrOH through an in-situ N-alkylation/oxidation process. This makes EtOH/nPrOH an economical and environmentally friendly precursor of alkenes as well as the solvent. |
| Keyword | Quinolines Nitrogen Heterocycles Iron Homogeneous Catalysis Alcohols Cascade Reactions |
| Subject Area | 物理化学与绿色催化 |
| DOI | 10.1002/ejoc.201601343 |
| Funding Organization | the Chinese Academy of Sciences;the National Natural Science Foundation of China (21133011;21373246;21522309) |
| Indexed By | SCI |
| If | 2.834 |
| Language | 英语 |
| Funding Project | 均相催化课题组 |
| compositor | 第一作者单位 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.licp.cn/handle/362003/21428 |
| Collection | 羰基合成与选择氧化国家重点实验室（OSSO） 苏州研究院 |
| Corresponding Author | Li FW(李福伟) |
| Affiliation | 1.Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Oxo Synth & Select Oxidat, Suzhou Res Inst, Lanzhou 730000, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| Recommended Citation GB/T 7714 | Li XJ,Xing Q,Li P,et al. Three-Component Povarov Reaction with Alcohols as Alkene Precursors: Efficient Access to 2-Arylquinolines[J]. European Journal of Organic Chemistry,2017,2017(3):618-625. |
| APA | Li XJ,Xing Q,Li P,Zhao JJ,Li FW,&李福伟.(2017).Three-Component Povarov Reaction with Alcohols as Alkene Precursors: Efficient Access to 2-Arylquinolines.European Journal of Organic Chemistry,2017(3),618-625. |
| MLA | Li XJ,et al."Three-Component Povarov Reaction with Alcohols as Alkene Precursors: Efficient Access to 2-Arylquinolines".European Journal of Organic Chemistry 2017.3(2017):618-625. |
| Files in This Item: | ||||||
| File Name/Size | DocType | Version | Access | License | ||
| Li_et_al-2017-Europe（1284KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | View Application Full Text | |
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