A three-dimensional graphene oxide supramolecularhydrogel for infrared light-responsive cascade releaseof two anticancer drugs
Department中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室
Ha W(哈伟)1; Zhao XB(赵晓博)1; Jiang K(姜侃)1; Kang Y(康洋)2; Chen J(陈娟)1; Li BJ(李帮经)2; Shi YP(师彦平)1; Shi YP(师彦平); Li BJ(李帮经)
2016
Source PublicationChemical Communications
ISSN1359-7345
Volume52Issue:100Pages:14384-14387
Abstract

A three dimensional supramolecular hydrogel consisting of prodrug-modified graphene oxide and α-cyclodextrin was developed. This hydrogel with a well-ordered interior microstructure integrated hydrophobic and hydrophilic anticancer drugs into a single multifunctional platform, and underwent a gel–sol transition leading to cascade release of two drugs in an on-demand fashion upon NIR light irradiation.

Subject Area分析化学与药物化学
DOI10.1039/c6cc08123a
Funding Organizationthe National Natural Science Foundation of China (Grant No. 21405164;21375136;21575150);the top priority program of ‘‘One-Three-Five’’ Strategic Planning of Lanzhou Institute of Chemical Physics, CAS
Indexed BySCI
If6.319
Language英语
Funding Project药物化学成分研究组
compositor第一作者单位
Citation statistics
Cited Times:29[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.licp.cn/handle/362003/21050
Collection中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室
Corresponding AuthorShi YP(师彦平); Li BJ(李帮经)
Affiliation1.Key Laboratory of Chemistry of Northwestern Plant Resources of CAS and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, P. R. China
2.Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, P. R. China
Recommended Citation
GB/T 7714
Ha W,Zhao XB,Jiang K,et al. A three-dimensional graphene oxide supramolecularhydrogel for infrared light-responsive cascade releaseof two anticancer drugs[J]. Chemical Communications,2016,52(100):14384-14387.
APA Ha W.,Zhao XB.,Jiang K.,Kang Y.,Chen J.,...&李帮经.(2016).A three-dimensional graphene oxide supramolecularhydrogel for infrared light-responsive cascade releaseof two anticancer drugs.Chemical Communications,52(100),14384-14387.
MLA Ha W,et al."A three-dimensional graphene oxide supramolecularhydrogel for infrared light-responsive cascade releaseof two anticancer drugs".Chemical Communications 52.100(2016):14384-14387.
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