| Synthesis of Tetrahydropyridine Derivatives through a Modular Assembly Reaction Using 3,4-Dihydropyran as Dual Substrate and Template | |
| Department | OSSO国家重点实验室 |
| Sun, Shaohuan1; Cheng, Cheng1; Yang, Jian1; Taheri, Amir1; Jiang, Dan1; Zhang, Biao1; Gu YL(顾彦龙)1,2; Gu YL(顾彦龙) | |
| 2014 | |
| Source Publication | Organic Letters
 |
| ISSN | 1523-7060 |
| Volume | 16Issue:17Pages:4520-4523 |
| Abstract | A concise method to synthesize 1,2,3,4-tetrahydropyridines is described that involves the use of 2-alkoxy-3,4-dihydropyran as a modular precursor to react with aniline and a nucleophile. In this method, the heteroatom of the dihydropyran ring was replaced by nitrogen of aniline while the nucleophile attached to its adjacent position. Various druglike polyheterocycles were prepared with this method by using NH2-containing 1,5- or 1,4-bisnucleophiles. |
| Subject Area | 物理化学与绿色催化 |
| DOI | 10.1021/ol5020637 |
| Funding Organization | the National Natural Science Foundation of China (21173089;21373093);the Chutian Scholar Program of the Hubei Provincial Government and the Cooperative Innovation Center of Hubei Province;the fundamental research funds the central universities in China (2014ZZGH019) |
| Indexed By | SCI |
| If | 6.364 |
| Language | 英语 |
| compositor | 第二作者单位 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.licp.cn/handle/362003/20336 |
| Collection | 羰基合成与选择氧化国家重点实验室（OSSO） |
| Corresponding Author | Gu YL(顾彦龙) |
| Affiliation | 1.Huazhong Univ Sci & Technol, Sch Chem & Chem Engn, Minist Educ, Key Lab Large Format Battery Mat & Syst, Wuhan 430074, Peoples R China 2.Lanzhou Inst Chem Phys, State Key Lab Oxo Synth & Select Oxidat, Lanzhou 730000, Peoples R China |
| Recommended Citation GB/T 7714 | Sun, Shaohuan,Cheng, Cheng,Yang, Jian,et al. Synthesis of Tetrahydropyridine Derivatives through a Modular Assembly Reaction Using 3,4-Dihydropyran as Dual Substrate and Template[J]. Organic Letters,2014,16(17):4520-4523. |
| APA | Sun, Shaohuan.,Cheng, Cheng.,Yang, Jian.,Taheri, Amir.,Jiang, Dan.,...&顾彦龙.(2014).Synthesis of Tetrahydropyridine Derivatives through a Modular Assembly Reaction Using 3,4-Dihydropyran as Dual Substrate and Template.Organic Letters,16(17),4520-4523. |
| MLA | Sun, Shaohuan,et al."Synthesis of Tetrahydropyridine Derivatives through a Modular Assembly Reaction Using 3,4-Dihydropyran as Dual Substrate and Template".Organic Letters 16.17(2014):4520-4523. |
| Files in This Item: | ||||||
| File Name/Size | DocType | Version | Access | License | ||
| ol5020637.pdf（808KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | View Application Full Text | |
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