Asymmetric Synthesis of Chiral Atropisomeric Bis-Aryl Organophosphorus from Menthyl H-Phosphinate | |
Department | OSSO国家重点实验室 |
Ma YN(马艳娜)1; Yang SD(杨尚东)1,2 | |
2016 | |
Source Publication | Chemical Record |
ISSN | 1527-8999 |
Volume | 16Issue:2Pages:977-986 |
Abstract | This review describes new methods for the synthesis of chiral monophosphine ligands with menthyl phenylphosphinate as a chiral auxiliary through asymmetric Suzuki-Miyaura cross-coupling reactions and asymmetric C–H functionalization. The chiral menthyl phenylphosphinate as a chiral auxiliary is easy to prepare and the menthyl group can easily be transformed into other functional groups, with the chiral center synchronously remaining. These methodologies provide highly efficient and practical strategies for the synthesis of novel axially chiral biaryl monophosphine oxides and their corresponding phosphines. Meanwhile, these reactions are easy to handle and exhibit wide scope for substrates with excellent diastereomeric ratios. |
Keyword | Asymmetric C-h Functionalization Asymmetric Suzuki-miyaura Cross-coupling Chiral Auxiliaries Menthyl Phenylphosphinate Phosphine Ligands |
Subject Area | 物理化学与绿色催化 |
DOI | 10.1002/tcr.201500242 |
Funding Organization | the NSFC (Nos. 21272100;21472076) |
Indexed By | SCI |
If | 3.855 |
Language | 英语 |
compositor | 第二作者单位 |
Citation statistics | |
Document Type | 期刊论文 |
Identifier | http://ir.licp.cn/handle/362003/20096 |
Collection | 羰基合成与选择氧化国家重点实验室(OSSO) |
Affiliation | 1.Lanzhou Univ, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China 2.Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Oxo Synth & Select Oxidat, Lanzhou 730000, Peoples R China |
Recommended Citation GB/T 7714 | Ma YN,Yang SD. Asymmetric Synthesis of Chiral Atropisomeric Bis-Aryl Organophosphorus from Menthyl H-Phosphinate[J]. Chemical Record,2016,16(2):977-986. |
APA | Ma YN,&Yang SD.(2016).Asymmetric Synthesis of Chiral Atropisomeric Bis-Aryl Organophosphorus from Menthyl H-Phosphinate.Chemical Record,16(2),977-986. |
MLA | Ma YN,et al."Asymmetric Synthesis of Chiral Atropisomeric Bis-Aryl Organophosphorus from Menthyl H-Phosphinate".Chemical Record 16.2(2016):977-986. |
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LZ01029057.pdf(717KB) | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | View Application Full Text |
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