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Lewis Acid Catalyzed [4+3] Cycloaddition of Propargylic Alcohols with Azides
Department固体润滑国家重点实验室
Han, Ya-Ping1; Song XR(宋贤荣)2; Qiu, Yi-Feng1; Zhang, Heng-Rui1; Li, Lian-Hua1; Jin, Dong-Po1; Sun, Xiao-Qing1; Liu XY(刘雪原)1; Liang YM(梁永民)1,3; Liang YM(梁永民)
2016
Source PublicationOrganic Letters
ISSN1523-7060
Volume18Issue:5Pages:940-943
Abstract

An unprecedented Lewis acid catalyzed [4 + 3] cycloaddition reaction is described that provides a straightforward route to polycyclic products containing an imine-based indole azepine scaffold, starting from readily available internal tertiary alkynols and azides. This cycloaddition protocol provides efficient and atom-economical access to a new class of fascinating imine-containing products in satisfactory yields, which has shown good application in the construction of seven-membered N-heterocycles.

Subject Area材料科学与物理化学
DOI10.1021/acs.orglett.5b03657
Funding Organizationthe National Natural Science Foundation (NSF 21272101;21472073);the "111" Project;J1103307;Program for Changjiang Scholars;the Fundamental Research Funds for the Central Universities (lzujbky-2014-194);Innovative Research Team in University (IRT1138)
Indexed BySCI
If6.579
Language英语
compositor第三作者单位
Citation statistics
Cited Times:53[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.licp.cn/handle/362003/19778
Collection固体润滑国家重点实验室(LSL)
Corresponding AuthorLiang YM(梁永民)
Affiliation1.Lanzhou Univ, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China
2.Jiangxi Sci Technol Normal Univ, Jiangxi Key Lab Organ Chem, Nanchang 330013, Peoples R China
3.Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Solid Lubricat, Lanzhou 730000, Peoples R China
Recommended Citation
GB/T 7714
Han, Ya-Ping,Song XR,Qiu, Yi-Feng,et al. Lewis Acid Catalyzed [4+3] Cycloaddition of Propargylic Alcohols with Azides[J]. Organic Letters,2016,18(5):940-943.
APA Han, Ya-Ping.,Song XR.,Qiu, Yi-Feng.,Zhang, Heng-Rui.,Li, Lian-Hua.,...&梁永民.(2016).Lewis Acid Catalyzed [4+3] Cycloaddition of Propargylic Alcohols with Azides.Organic Letters,18(5),940-943.
MLA Han, Ya-Ping,et al."Lewis Acid Catalyzed [4+3] Cycloaddition of Propargylic Alcohols with Azides".Organic Letters 18.5(2016):940-943.
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