Amino-terminated ionic liquid modified graphene oxide coated silica composite stationary phase for hydrophilic interaction chromatography | |
Department | 中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室 |
Liu HM(刘后梅)1,2,3; Guo Y(郭勇)1,2; Wang XS(王旭生)1,2; Liang XJ(梁晓静)1,2; Liu X(刘霞)1,2; Liang XJ(梁晓静); Liu X(刘霞) | |
2014 | |
Source Publication | RSC Advances |
ISSN | 2046-2069 |
Volume | 4Issue:70Pages:37381-37388 |
Abstract | In this study, an amino-terminated ionic liquid modified graphene oxide coated silica composite stationary phase (IL@GO@SiO2) has been synthesized and applied for the separation of B vitamins, amino acids and aromatic acids in hydrophilic interaction chromatography (HILIC) mode. The synthesized novel material was characterized by elemental analysis, field emission scanning electron microscopy and infrared spectroscopy. The chromatographic properties of the IL@GO@ SiO2 phase were compared with those of the pure silica phase, amino-terminated ionic liquid modified silica phase, and graphene oxide modified silica phase. The results show that IL@GO@SiO2 exhibits the best separation efficiency compared to the other three phases, which is ascribed to the existence of the multiple interactions, i.e., electrostatic interactions, π–π interactions and dipole–dipole interactions between the resulting stationary phase and the analytes. The differences between the four stationary phases illustrate that the combination of IL and GO plays an important role in improving the separation efficiency. |
Subject Area | 分析化学与药物化学 |
DOI | 10.1039/c4ra03432e |
Funding Organization | the National Natural Science Foundation of China (21105107;21175143);National Science & Technology Major Project of China (2011ZX05011) |
Indexed By | SCI |
If | 3.840 |
Language | 英语 |
Funding Project | 药物分离材料研究组 |
compositor | 第一作者单位 |
Citation statistics | |
Document Type | 期刊论文 |
Identifier | http://ir.licp.cn/handle/362003/19264 |
Collection | 中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室 |
Corresponding Author | Liang XJ(梁晓静); Liu X(刘霞) |
Affiliation | 1.Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Chem Northwestern Plant Resources, Lanzhou 730000, Peoples R China 2.Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Nat Med Gansu Prov, Lanzhou 730000, Peoples R China 3.Chinese Acad Sci, Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
Recommended Citation GB/T 7714 | Liu HM,Guo Y,Wang XS,et al. Amino-terminated ionic liquid modified graphene oxide coated silica composite stationary phase for hydrophilic interaction chromatography[J]. RSC Advances,2014,4(70):37381-37388. |
APA | Liu HM.,Guo Y.,Wang XS.,Liang XJ.,Liu X.,...&刘霞.(2014).Amino-terminated ionic liquid modified graphene oxide coated silica composite stationary phase for hydrophilic interaction chromatography.RSC Advances,4(70),37381-37388. |
MLA | Liu HM,et al."Amino-terminated ionic liquid modified graphene oxide coated silica composite stationary phase for hydrophilic interaction chromatography".RSC Advances 4.70(2014):37381-37388. |
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c4ra03432e.pdf(591KB) | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | View Application Full Text |
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