| N-Heterocyclic carbene catalyzed intramolecular nucleophilic addition of carbonyl anion equivalents to enol ethers | |
| Department | 羰基合成与选择氧化国家重点实验室 |
| He JM(何金梅); Tang SC(唐寿初); Liu J(刘剑); Su YP(苏瀛鹏); Pan XF(潘鑫复); She XG(厍学功) | |
| 2008 | |
| Source Publication | Tetrahedron
 |
| ISSN | 0040-4020 |
| Volume | 64Pages:8797-8800 |
| Abstract | The intramolecular nucleophilic addition reaction of acyl anion equivalents to enol ethers is described, which was catalyzed by N-heterocyclic carbenes generated in situ from readily available thiazolium salt. In this transformation, benzofuranones were obtained in excellent yield. In combination with our previous work, the precise mechanistic elucidation for the formation of benzofuranones has been further investigated. A labeling experiment implied that the transformation proceeds through a nucleophilic addition mechanism. |
| Subject Area | 物理化学 |
| Funding Organization | the Special Doctorial Program Funds of the Ministry of Education of China (20040730008);NSFC (QT program, No. 20572037);NCET-05-0879;the key grant project of Chinese ministry of Education (No. 105169);and Gansu Science Foundation (3ZS051-A25-004) |
| Indexed By | SCI |
| Language | 英语 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.licp.cn/handle/362003/1914 |
| Collection | 羰基合成与选择氧化国家重点实验室（OSSO） |
| Corresponding Author | She XG(厍学功) |
| Recommended Citation GB/T 7714 | He JM,Tang SC,Liu J,et al. N-Heterocyclic carbene catalyzed intramolecular nucleophilic addition of carbonyl anion equivalents to enol ethers[J]. Tetrahedron,2008,64:8797-8800. |
| APA | 何金梅,唐寿初,刘剑,苏瀛鹏,潘鑫复,&厍学功.(2008).N-Heterocyclic carbene catalyzed intramolecular nucleophilic addition of carbonyl anion equivalents to enol ethers.Tetrahedron,64,8797-8800. |
| MLA | 何金梅,et al."N-Heterocyclic carbene catalyzed intramolecular nucleophilic addition of carbonyl anion equivalents to enol ethers".Tetrahedron 64(2008):8797-8800. |
| Files in This Item: | ||||||
| File Name/Size | DocType | Version | Access | License | ||
| 20_Tetrahedron,2008,（494KB） | 开放获取 | License | View Application Full Text | |||
Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.
Edit Comment