| Chiral diphosphites derived from (1R,2R)-trans-1,2-cyclohexanediol: a new class of ligands for asymmetric hydrogenations | |
| Department | OSSO国家重点实验室 |
Pang ZB(逄增波)1,2 ; Li HF(李海峰)1; Tian M(田密)1,2; Wang LL(王来来)1; Wang LL(王来来)
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| 2015 | |
| Source Publication | Tetrahedron: Asymmetry
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| ISSN | 0957-4166 |
| Volume | 26Issue:24Pages:1389-1393 |
| Abstract | A series of novel chiral diphosphite ligands was easily prepared in a few steps from commercial (1R,2R)-trans-1,2-cyclohexanediol as the chiral source, and successfully employed in the Rh-catalyzed asymmetric hydrogenation of alpha,beta-unsaturated carboxylic acid derivatives and enamides with up to 99% ee for dimethyl itaconate and enamides and with up to 94% ee for alpha-dehydroamino acid esters. The stereochemically matched combination of (1R,2R)-trans-1,2-cyclohexanediol backbone and (S)-binaphthyl in the ligand (1R,2R)-bis[(S)-1,1'-binaphthyl-2,2'-diyllphosphitecyclohexanediol, was essential for inducing high enantioselectivity. Moreover, the sense of enantiodiscrimination of the products was mainly determined by the configuration of the binaphthyl moieties. |
| Subject Area | 物理化学与绿色催化 |
| DOI | 10.1016/j.tetasy.2015.10.020 |
| Funding Organization | the National Natural Science Foundation of China (Nos. 20773147;21073211;21174155) |
| Indexed By | SCI |
| If | 2.108 |
| Language | 英语 |
| Funding Project | 有机功能材料研究组 |
| compositor | 第一作者单位 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.licp.cn/handle/362003/19027 |
| Collection | 羰基合成与选择氧化国家重点实验室（OSSO） |
| Corresponding Author | Wang LL(王来来) |
| Affiliation | 1.Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Oxo Synth & Select Oxidat, Lanzhou 730000, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100039, Peoples R China |
| Recommended Citation GB/T 7714 | Pang ZB,Li HF,Tian M,et al. Chiral diphosphites derived from (1R,2R)-trans-1,2-cyclohexanediol: a new class of ligands for asymmetric hydrogenations[J]. Tetrahedron: Asymmetry,2015,26(24):1389-1393. |
| APA | Pang ZB,Li HF,Tian M,Wang LL,&王来来.(2015).Chiral diphosphites derived from (1R,2R)-trans-1,2-cyclohexanediol: a new class of ligands for asymmetric hydrogenations.Tetrahedron: Asymmetry,26(24),1389-1393. |
| MLA | Pang ZB,et al."Chiral diphosphites derived from (1R,2R)-trans-1,2-cyclohexanediol: a new class of ligands for asymmetric hydrogenations".Tetrahedron: Asymmetry 26.24(2015):1389-1393. |
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| Tetrahedron Asymmetr（756KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | View Application Full Text | |
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