| Decarboxylative Alkylcarboxylation of alpha,beta-Unsaturated Acids Enabled by Copper-Catalyzed Oxidative Coupling | |
| Department | OSSO国家重点实验室 |
Gao B(高宝); Xie YJ(谢银君); Shen ZQ(沈志强) ; Yang L(杨磊); Huang HM(黄汉民); Huang HM(黄汉民)
| |
| 2015 | |
| Source Publication | Organic Letters
 |
| ISSN | 1523-7060 |
| Volume | 17Issue:20Pages:4968-4971 |
| Abstract | A facile and general method for coppercatalyzed decarboxylative alkylcarboxylation of cinnamic acids with dimethyl 2,2'-azobis(2-methylpropionate) has been developed. The scope and versatility of the reaction was demonstrated, and a broad range of substrates bearing electron-donating and -withdrawing groups on the aromatic rings were all compatible with this reaction to provide desired beta,gamma-unsaturated esters in moderate to good yields. Moreover, alpha,beta-unsaturated acids with a carbonyl group on the gamma-position of acrylic acids also smoothly proceeded to furnish the desired products in good yields. |
| Subject Area | 有机化学 |
| DOI | 10.1021/acs.orglett.5b02382 |
| Funding Organization | the Chinese Academy of Sciences;the National Natural Science Foundation of China (21222203;21372231;21133011) |
| Indexed By | SCI |
| If | 6.364 |
| Language | 英语 |
| Funding Project | 有机功能材料研究组 |
| compositor | 第一作者单位 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.licp.cn/handle/362003/18644 |
| Collection | 羰基合成与选择氧化国家重点实验室（OSSO） |
| Corresponding Author | Huang HM(黄汉民) |
| Affiliation | Chinese Acad Sci, State Key Lab Oxo Synth & Select Oxidat, Lanzhou Inst Chem Phys, Lanzhou 730000, Peoples R China |
| Recommended Citation GB/T 7714 | Gao B,Xie YJ,Shen ZQ,et al. Decarboxylative Alkylcarboxylation of alpha,beta-Unsaturated Acids Enabled by Copper-Catalyzed Oxidative Coupling[J]. Organic Letters,2015,17(20):4968-4971. |
| APA | Gao B,Xie YJ,Shen ZQ,Yang L,Huang HM,&黄汉民.(2015).Decarboxylative Alkylcarboxylation of alpha,beta-Unsaturated Acids Enabled by Copper-Catalyzed Oxidative Coupling.Organic Letters,17(20),4968-4971. |
| MLA | Gao B,et al."Decarboxylative Alkylcarboxylation of alpha,beta-Unsaturated Acids Enabled by Copper-Catalyzed Oxidative Coupling".Organic Letters 17.20(2015):4968-4971. |
| Files in This Item: | ||||||
| File Name/Size | DocType | Version | Access | License | ||
| Org. Lett. 2015, 17,（746KB） | 期刊论文 | 出版稿 | 开放获取 | CC BY-NC-SA | View Application Full Text | |
Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.
Edit Comment