| A new highly oxygenated daphnane diterpene esters from the flower buds of Daphne genkwa | |
| Department | 中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室 |
Jiang HL(姜海龙)1,2,4; Wang R(王瑞)1,2 ; Li, Jian-Yong3; Shi YP(师彦平)1,2; Shi YP(师彦平)
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| 2015 | |
| Source Publication | Natural Product Research
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| ISSN | 1478-6419 |
| Volume | 29Issue:20Pages:1878-1883 |
| Abstract | The phytochemical investigation of the flower buds of Daphne genkwa yielded eight highly oxygenated daphnane-type diterpene esters, including a new one, genkwanine N 20-palmitate (1) and seven known ones (2-8). The molecular structures of the isolated compounds were elucidated on the basis of extensive spectroscopic analysis, including UV, IR, NMR, and MS, and comparison with literature data. Furthermore, compound 1 showed potential cytotoxic activity in vitro, against A549 and Hep G2 tumour cell lines. |
| Keyword | Cytotoxicity Daphnane Diterpenoid Daphne Genkwa |
| Subject Area | 分析化学与药物化学 |
| DOI | 10.1080/14786419.2015.1009459 |
| Funding Organization | National Natural Science Foundation of China (grant number 81303202);(grant number 21375136);the open fund of the New Animal Drug Project of Gansu Province and the Key Laboratory of Veterinary Pharmaceutical Development of the Ministry of Agriculture (grant number 1610322011011) |
| Indexed By | SCI |
| If | 1.057 |
| Language | 英语 |
| Funding Project | 药物化学成分研究组 |
| compositor | 第一作者单位 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.licp.cn/handle/362003/18579 |
| Collection | 中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室 |
| Corresponding Author | Shi YP(师彦平) |
| Affiliation | 1.Chinese Acad Sci, Key Lab Chem Northwestern Plant Resources CAS, Lanzhou 730000, Peoples R China 2.Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Nat Med Gansu Prov, Lanzhou 730000, Peoples R China 3.Lanzhou Inst Husb & Pharmaceut Sci CAAS, Key Lab New Anim Drug Project, Gansu Prov & Key Lab Vet Pharmaceut Dev, Minist Agr, Lanzhou 730050, Peoples R China 4.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| Recommended Citation GB/T 7714 | Jiang HL,Wang R,Li, Jian-Yong,et al. A new highly oxygenated daphnane diterpene esters from the flower buds of Daphne genkwa[J]. Natural Product Research,2015,29(20):1878-1883. |
| APA | Jiang HL,Wang R,Li, Jian-Yong,Shi YP,&师彦平.(2015).A new highly oxygenated daphnane diterpene esters from the flower buds of Daphne genkwa.Natural Product Research,29(20),1878-1883. |
| MLA | Jiang HL,et al."A new highly oxygenated daphnane diterpene esters from the flower buds of Daphne genkwa".Natural Product Research 29.20(2015):1878-1883. |
| Files in This Item: | ||||||
| File Name/Size | DocType | Version | Access | License | ||
| 15-NPR-2015(JiangHL)（204KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | View Application Full Text | |
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