Construction of an all-substituted pyrrolidine derivative with multiple stereogenic centers and Betti-base-derived gamma-amino alcohols by [1,2]-Wittig rearrangement | |
Department | OSSO国家重点实验室 |
Wang, Cai-Yun1; Dong, Cheng1; Zheng ZJ(郑战江)1; Xu, Zheng1; Yang KF(杨科芳)1; Xu LW(徐利文)1,2; Zheng ZJ(郑战江); Xu LW(徐利文) | |
2015 | |
Source Publication | RSC Advances |
ISSN | 2046-2069 |
Volume | 5Issue:69Pages:55819-55824 |
Abstract | A new class of substituted γ-amino alcohols and downstream pyrrolidine derivatives have been synthesized successfully from simple 1-phenyl-ethylamine, in which a representative all-substituted pyrrolidine derivative with multiple stereogenic centers was obtained by highly diastereoselective [1,2]-Wittig rearrangement and intramolecular cyclization with perfect chirality transfer (up to >99.9% de) and good yields. |
Subject Area | 物理化学与绿色催化 |
DOI | 10.1039/c5ra09145d |
Funding Organization | the National Natural Science Founder of China (No. 21173064;51303043;21472031);Zhejiang Provincial Natural Science Foundation of China (LR14B030001) |
Indexed By | SCI |
If | 3.840 |
Language | 英语 |
compositor | 第二作者单位 |
Citation statistics | |
Document Type | 期刊论文 |
Identifier | http://ir.licp.cn/handle/362003/18517 |
Collection | 羰基合成与选择氧化国家重点实验室(OSSO) |
Corresponding Author | Zheng ZJ(郑战江); Xu LW(徐利文) |
Affiliation | 1.Hangzhou Normal Univ, Key Lab Organosilicon Chem & Mat Technol, Minist Educ MOE, Hangzhou 311121, Zhejiang, Peoples R China 2.Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Oxo Synth & Select Oxidat, Lanzhou 730000, Peoples R China |
Recommended Citation GB/T 7714 | Wang, Cai-Yun,Dong, Cheng,Zheng ZJ,et al. Construction of an all-substituted pyrrolidine derivative with multiple stereogenic centers and Betti-base-derived gamma-amino alcohols by [1,2]-Wittig rearrangement[J]. RSC Advances,2015,5(69):55819-55824. |
APA | Wang, Cai-Yun.,Dong, Cheng.,Zheng ZJ.,Xu, Zheng.,Yang KF.,...&徐利文.(2015).Construction of an all-substituted pyrrolidine derivative with multiple stereogenic centers and Betti-base-derived gamma-amino alcohols by [1,2]-Wittig rearrangement.RSC Advances,5(69),55819-55824. |
MLA | Wang, Cai-Yun,et al."Construction of an all-substituted pyrrolidine derivative with multiple stereogenic centers and Betti-base-derived gamma-amino alcohols by [1,2]-Wittig rearrangement".RSC Advances 5.69(2015):55819-55824. |
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c5ra09145d.pdf(1112KB) | 期刊论文 | 出版稿 | 开放获取 | CC BY-NC-SA | View Application Full Text |
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