| EVALUATION OF THE QUALITY OF ANGELICA SINENSIS BY HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY | |
| Department | 中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室 |
Wang ZZ(王振忠)1,2,3 ; Shao SJ(邵士俊)1,2; Shao SJ(邵士俊)
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| 2014 | |
| Source Publication | Analytical Letters
 |
| ISSN | 0003-2719 |
| Volume | 47Issue:18Pages:2857-2870 |
| Abstract | Quality control and consistent quality are prerequisites to guarantee the safety and efficacy of pharmaceutical preparations and dietary supplements. In this paper, the intra-and inter-annual consistency and stability of Angelica sinensis (Oliv.) Diels, cultivated according to Good Agricultural Practices (GAP) in the main production areas of China, were evaluated by high-performance liquid chromatographic fingerprints composed of twenty-four common components. Subsequently, thirteen compounds were identified in the chromatograms using diode array detection and mass spectrometry. Z-Ligustilide, senkyunolide H, senkyunolide I, and ferulic acid were determined to evaluate the distribution of chemical components. In addition, robust principal component analysis was applied to further evaluate the samples, and four discriminatory "markers'' among the common twenty-four were pinpointed by the loading plots that were used to distinguish quality differences of Angelica sinensis from different harvest years. |
| Keyword | Angelica Sinensis High-performance Liquid Chromatography (Hplc) Fingerprint High-performance Liquid Chromatography-diode Array Detector-electrospray Ionization Mass Spectrometry (Hplc-dad-esi-ms) Robust Principal Component Analysis |
| Subject Area | 分析化学与药物化学 |
| DOI | 10.1080/00032719.2014.928880 |
| Funding Organization | the National Key Technology Research and Development Program of the Ministry of Science and Technology of China (Grant No. 2007BAI37B05);the major goals/breakthroughs program of “One-three-Five” Strategic Planning of Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences |
| Indexed By | SCI |
| If | 1.030 |
| Language | 英语 |
| Funding Project | 药物分子识别研究组 |
| compositor | 第一作者单位 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.licp.cn/handle/362003/18297 |
| Collection | 中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室 |
| Corresponding Author | Shao SJ(邵士俊) |
| Affiliation | 1.Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Chem Northwestern Plant Resources, Lanzhou 730000, Peoples R China 2.Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Nat Med Gansu Prov, Lanzhou 730000, Peoples R China 3.Univ Chinese Acad Sci, Beijing, Peoples R China |
| Recommended Citation GB/T 7714 | Wang ZZ,Shao SJ,Shao SJ. EVALUATION OF THE QUALITY OF ANGELICA SINENSIS BY HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY[J]. Analytical Letters,2014,47(18):2857-2870. |
| APA | Wang ZZ,Shao SJ,&邵士俊.(2014).EVALUATION OF THE QUALITY OF ANGELICA SINENSIS BY HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY.Analytical Letters,47(18),2857-2870. |
| MLA | Wang ZZ,et al."EVALUATION OF THE QUALITY OF ANGELICA SINENSIS BY HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY".Analytical Letters 47.18(2014):2857-2870. |
| Files in This Item: | ||||||
| File Name/Size | DocType | Version | Access | License | ||
| LZ01027802.pdf（363KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | View Application Full Text | |
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