| Phenolic Derivatives and Free-Radical-Scavenging Activity from Ixeridium gracile (DC.) SHIH | |
| Department | 甘肃省天然药物重点实验室 |
Ma XM(马雪梅); Liu Y(刘勇); Shi YP(师彦平)
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| 2007 | |
| Source Publication | Chemistry & Biodiversity
 |
| ISSN | 1612-1872 |
| Volume | 4Pages:2172-2181 |
| Abstract | Phytochemical investigation of the Tibetan medicinal plant Ixeridium gracile resulted in the isolation and identification of twelve flavonoids and two coumarins, compounds 1–14, the dimeric 92a,3a-epoxy- 5,7,3’,4’-tetrahydroxyflavan-(4b!8)-epicatechin; (1) being a new constituent. The free-radical-scavenging potentials of different extract fractions as well as of the pure compounds towards the DPPH (1,1- diphenyl-2-picrylhydrazyl) radical were evaluated, and are discussed in terms of structure–activity relationship (SAR). The flavonoids were found to be the major constituents contributing to the freeradical- scavenging activity of I. gracile, but the high concentration of coumarins additionally contributed to the observed activity. |
| Subject Area | 分析化学与药物化学 |
| Funding Organization | the National Natural Science Foundation of China (No. 20372029;20475057);the National Natural Science Foundation of Gansu Province (No. 3ZS051-A25-077) |
| Indexed By | SCI |
| Language | 英语 |
| Funding Project | 药物化学成分研究组 |
| Document Type | 期刊论文 |
| Identifier | http://ir.licp.cn/handle/362003/1413 |
| Collection | 中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室 |
| Corresponding Author | Shi YP(师彦平) |
| Recommended Citation GB/T 7714 | Ma XM,Liu Y,Shi YP. Phenolic Derivatives and Free-Radical-Scavenging Activity from Ixeridium gracile (DC.) SHIH[J]. Chemistry & Biodiversity,2007,4:2172-2181. |
| APA | 马雪梅,刘勇,&师彦平.(2007).Phenolic Derivatives and Free-Radical-Scavenging Activity from Ixeridium gracile (DC.) SHIH.Chemistry & Biodiversity,4,2172-2181. |
| MLA | 马雪梅,et al."Phenolic Derivatives and Free-Radical-Scavenging Activity from Ixeridium gracile (DC.) SHIH".Chemistry & Biodiversity 4(2007):2172-2181. |
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| Phenolic Derivatives（110KB） | 开放获取 | License | View Application Full Text | |||
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