| ent-Kaurane and ent-Pimarane Diterpenoids from Siegesbeckia pubescens | |
| Department | 甘肃省天然药物重点实验室 |
Wang R(王瑞) ; Chen WH(陈文豪); Shi YP(师彦平)
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| 2010 | |
| Source Publication | J. Nat. Prod.
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| ISSN | 0163-3864 |
| Volume | 73Pages:17-21 |
| Abstract | Phytochemical investigation of the above-ground parts of Siegesbeckia pubescens yielded 25 diterpenoids, including five new ent-pimarane diterpenoids (1-3, 11, and 12) and four new ent-kaurane diterpenoids (13-16). The structures and relative configurations of the new compounds were elucidated by comprehensive spectroscopic analysis and by comparison of their NMR data with those of related compounds. Single-crystal X-ray diffraction analysis confirmed the structures of 8, 13, and 14. Seven of these diterpenoids were evaluated for cytotoxic activity against HSC-T6, HeLa, and B16 cell lines. Compounds 11 and 14 exhibited moderate cytotoxicity. |
| Subject Area | 分析化学与药物化学 |
| Funding Organization | the National Natural Science Foundation of China (No.NSFC20621091);the National 863 Program of China( No.2007AA09Z403);the National Key Technology Research and Development Program of China (No.2007BAI37B05) |
| Indexed By | SCI |
| Language | 英语 |
| Funding Project | 药物化学成分研究组 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.licp.cn/handle/362003/1206 |
| Collection | 中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室 |
| Corresponding Author | Shi YP(师彦平) |
| Recommended Citation GB/T 7714 | Wang R,Chen WH,Shi YP. ent-Kaurane and ent-Pimarane Diterpenoids from Siegesbeckia pubescens[J]. J. Nat. Prod.,2010,73:17-21. |
| APA | 王瑞,陈文豪,&师彦平.(2010).ent-Kaurane and ent-Pimarane Diterpenoids from Siegesbeckia pubescens.J. Nat. Prod.,73,17-21. |
| MLA | 王瑞,et al."ent-Kaurane and ent-Pimarane Diterpenoids from Siegesbeckia pubescens".J. Nat. Prod. 73(2010):17-21. |
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