| Simultaneous Determination of Dopamine and Ascorbic Acid Using the Nano-Gold Self-Assembled Glassy Carbon Electrode | |
| Department | 甘肃省天然药物重点实验室 |
Hu GZ(胡广志); Guo Y(郭勇) ; Shao SJ(邵士俊)
| |
| 2009 | |
| Source Publication | Electroanalysis
 |
| ISSN | 1040-0397 |
| Volume | 21Issue:10Pages:1200-1206 |
| Abstract | Electrochemical behavior of dopamine (DA) was investigated at the gold nanoparticles self-assembled glassy carbon electrode (GNP/LC/GCE), which was fabricated by self-assembling gold nanoparticles on the surface of l-cysteine (LC) modified glassy carbon electrode (GCE) via successive cyclic voltammetry (CV). A pair of well-defined redox peaks of DA on the GNP/LC/GCE was obtained at Epa¼0.197 V and Epc¼0.146 V, respectively. And the peak separation between DA and AA is about 0.2 V, which is enough for simultaneous determination of DA and AA. The peak currents of DA and AA were proportional with their concentrations in the range of 6.0 10 8 – 8.5 10 5 mol L 1 and 1.0 10 6 – 2.5 10 3 mol L 1, with the detection limit of 2.0 10 8 mol L 1 and 3.0 10 7 mol L 1 (S/N¼3),respectively. The modified electrode exhibits an excellent reproducibility, sensibility and stability for simultaneous determination of DA and AA in human serum with satisfactory result. |
| Keyword | Gold Nanoparticles Self-assembled Electrode Dopamine Ascorbic Acid Simultaneous Determination Differential Pulse Voltammetry |
| Subject Area | 分析化学与药物化学 |
| Funding Organization | The National Nature Science Foundation of China (No. 20672121) |
| Indexed By | SCI |
| Language | 英语 |
| Funding Project | 药物分子识别研究组 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.licp.cn/handle/362003/1187 |
| Collection | 中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室 |
| Corresponding Author | Shao SJ(邵士俊) |
| Recommended Citation GB/T 7714 | Hu GZ,Guo Y,Shao SJ. Simultaneous Determination of Dopamine and Ascorbic Acid Using the Nano-Gold Self-Assembled Glassy Carbon Electrode[J]. Electroanalysis,2009,21(10):1200-1206. |
| APA | 胡广志,郭勇,&邵士俊.(2009).Simultaneous Determination of Dopamine and Ascorbic Acid Using the Nano-Gold Self-Assembled Glassy Carbon Electrode.Electroanalysis,21(10),1200-1206. |
| MLA | 胡广志,et al."Simultaneous Determination of Dopamine and Ascorbic Acid Using the Nano-Gold Self-Assembled Glassy Carbon Electrode".Electroanalysis 21.10(2009):1200-1206. |
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